Unlike statins and red yeast rice extract, which prevent the body from making cholesterol, plant stanols keep the body from absorbing cholesterol. Hazen recommends plant stanols as another nonprescription way to help lower LDL cholesterol levels. If there is a significant jump in eosinophils, I recommend that the patient stops taking the supplements." Plant stanols to lower cholesterol levelsĭr. In general, when a patient takes a large amount of supplements, I also recommend getting a complete blood cell count with differential to check for eosinophilia − higher than the normal level of a type of white blood cells called eosinophils − or other abnormalities. Hazen states, “When I have a patient who is adamant about not wishing to take an FDA-cleared drug, but is agreeable to taking a "natural" intervention to lower LDL cholesterol, I have, on these rare occasions, used red yeast rice extract and monitored the patient for side effects and ordered liver function tests. Using red yeast rice extract instead of prescription statinsĭr. It is not recommended to take red yeast rice extract and prescription statins together. It is important to talk to your doctor before taking red yeast rice extract or any other medication or supplement and to have regular follow-up visits with your doctor. A higher cost does not guarantee a better product. Also, different brands of the product may work better than others and there can even be differences among batches from the same manufacturer. The FDA made the companies stop this practice, as the altered product was no longer completely natural. In the past, some manufacturers of red yeast rice extract added chemically created lovastatin to boost the power to reduce LDL cholesterol levels. The lack of FDA regulation means the product could contain ingredients besides the extract that could cause side effects or safety issues. Red yeast rice extracts are not monitored by the FDA. Because the extract contains less lovastatin than prescription statins do, side effects are less common with the extract. These side effects include higher than normal liver function test results and muscle weakness (myopathy). Risks of red yeast rice extractīecause red yeast rice extract contains lovastatin, it can cause the same side effects as chemically created statins. But, the amount of lovastatin in the extract is much lower than the amount in the prescription drug. The lovastatin in the extract has the same chemical make-up as Mevacor, a cholesterol-lowering drug (statin) first developed by the drug company Merck. Red yeast rice extract naturally contains lovastatin, which keeps the body from making cholesterol. However, the fact that the study only involved Chinese patients makes it difficult to know if the results would be the same for people of other races and cultures who eat a different diet than the Chinese." Why does red yeast rice extract work to lower cholesterol? For this reason, the study is significant.
RED YEAST RICE COQ 10 TRIAL
Stanley Hazen, MD, PhD, Section Head of Preventive Cardiology & Rehabilitation at Cleveland Clinic, says, “To my knowledge, this trial is the only one of its kind monitoring hard outcomes like heart attack, stroke and death risk in a randomized trial with red yeast rice extract. They were also about a third less likely to need revascularization, such as angioplasty. The study showed that patients who took red yeast rice were 30-33% less likely to die from CAD or any other cause. Patients took part in the trial for an average of 5 years. Patients were randomly chosen to take at least 600 mg of red yeast rice extract twice a day or a placebo. All patients had coronary artery disease (CAD), and the study looked at how many people had a major cardiovascular event, like a heart attack, or died from CAD. The effects of red yeast rice extract were also tested in China in a study that included almost 5,000 patients. Studies in the United States have shown that high doses of red yeast rice extract (2.4 gm/day) can reduce your total cholesterol level as much as 20-25%, although usually less. Studies showing the benefits of red yeast rice extract Red yeast rice extract is a form of fermented rice developed in China. Adding red yeast rice extract to your diet can help lower your cholesterol levels, which reduces your risk of cardiovascular disease, like heart attack.
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